Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
nanomaterial aspect ratio/shape
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2019
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report date:
2019

Materials and methods

Principles of method if other than guideline:
Guidelines from NanoDefine are applied:
Method selection according to Gaillard et al., Nanoscale Adv., 2019, 1, 781
TEM image evaluation according to Verleysen et al., Materials 2019, 12, 2274; doi:10.3390/ma12142274
GLP compliance:
no
Type of method:
transmission electron microscopy
Details on methods and data evaluation:
Sample Preparation:
A suspension in ethanol was dispersed between two object slides and applied on a TEM grid

Test material

Constituent 1
Chemical structure
Reference substance name:
Barium bis[2-chloro-5-[(2-hydroxy-1-naphthyl)azo]toluene-4-sulphonate]
EC Number:
225-935-3
EC Name:
Barium bis[2-chloro-5-[(2-hydroxy-1-naphthyl)azo]toluene-4-sulphonate]
Cas Number:
5160-02-1
Molecular formula:
C17H13ClN2O4S.1/2Ba
IUPAC Name:
barium(2+) bis(5-chloro-2-[(1E)-2-(2-hydroxynaphthalen-1-yl)diazen-1-yl]-4-methylbenzene-1-sulfonate)
Test material form:
solid: nanoform

Data gathering

Instruments:
TEM: Thermo-Fisher Talos F200i 200kV
Calibration:
every 12 months with Mag*i*Cal sample
Reproducibility:
systematic error +/-3%

Results and discussion

Shape description
Key result
Shape:
other: mixtures of particles with different shapes
Remarks on result:
other: The material is assigned to the “MULTIMODAL” shape category.
Aspect ratio
Key result
Remarks on result:
other: D50= 2,2:1

Applicant's summary and conclusion

Conclusions:
The material is assigned to the “MULTIMODAL” shape category and the particles have a median aspect ratio of 2,2:1.