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Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
publication
Title:
De la toxicité de quelques esters|acryliques et méthacryliques de l'acrylamide et des polyacrylamides.
Author:
Paulet G, Vidal M
Year:
1975
Bibliographic source:
Arch. Mal. Prof. Med. Trav. Sec. Soc. 36 (1-2): 58-60 [in French, no English abstract]

Materials and methods

Principles of method if other than guideline:
other: no data
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
2-Propenoic acid, 2-methyl-, dodecyl ester purity not specified, but commercial grade assumed.
Specific details on test material used for the study:
2-Propenoic acid, 2-methyl dodecylester (CAS: 142-90-5)

Test animals

Species:
rat

Administration / exposure

Route of administration:
intraperitoneal

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
12 000 mg/kg bw

Applicant's summary and conclusion

Conclusions:
In a intraperitoneal acute toxicity study on Dodecyl methacrylate with rats, an LD50: 12 g/kg was observed.
Executive summary:

In a intraperitoneal acute toxicity study on Dodecyl methacrylate with rats, an LD50: 12 g/kg was observed.