Registration Dossier
Registration Dossier
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EC number: 205-570-6 | CAS number: 142-90-5
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- De la toxicité de quelques esters|acryliques et méthacryliques de l'acrylamide et des polyacrylamides.
- Author:
- Paulet G, Vidal M
- Year:
- 1 975
- Bibliographic source:
- Arch. Mal. Prof. Med. Trav. Sec. Soc. 36 (1-2): 58-60 [in French, no English abstract]
Materials and methods
- Principles of method if other than guideline:
- other: no data
- GLP compliance:
- no
Test material
- Reference substance name:
- Dodecyl methacrylate
- EC Number:
- 205-570-6
- EC Name:
- Dodecyl methacrylate
- Cas Number:
- 142-90-5
- Molecular formula:
- C16H30O2
- IUPAC Name:
- dodecyl 2-methylprop-2-enoate
- Details on test material:
- 2-Propenoic acid, 2-methyl-, dodecyl ester purity not specified, but commercial grade assumed.
Constituent 1
- Specific details on test material used for the study:
- 2-Propenoic acid, 2-methyl dodecylester (CAS: 142-90-5)
Test animals
- Species:
- rat
Administration / exposure
- Route of administration:
- intraperitoneal
Results and discussion
Effect levels
- Dose descriptor:
- LD50
- Effect level:
- 12 000 mg/kg bw
Applicant's summary and conclusion
- Conclusions:
- In a intraperitoneal acute toxicity study on Dodecyl methacrylate with rats, an LD50: 12 g/kg was observed.
- Executive summary:
In a intraperitoneal acute toxicity study on Dodecyl methacrylate with rats, an LD50: 12 g/kg was observed.
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