Registration Dossier
Registration Dossier
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EC number: 617-969-6 | CAS number: 87135-01-1
Endpoint summary
Administrative data
Description of key information
Additional information
Reliable short-term toxicity test results are available for freshwater fish (Oncorhynchus mykiss) , invertebrates (Daphnia magna) and algae (Pseudokirchnerella subcapitata) are available for 1,6-bis(trimethoxysilyl)hexane (CAS 87135-01-1). The relevant short-term values are:
Fish: LC50 (96 h): >100 mg/l; NOEC: ≥100 mg/l (nominal) (EC50 >74 mg/l when expressed in terms of concentration of the hydrolysis product, 1,6-bis(trihydroxysilyl)hexane).
Daphnia: EC50 (48 h): >100 mg/l; NOEC: ≥100 mg/l (nominal) (EC50 >74 mg/l when expressed in terms of concentration of the hydrolysis product, 1,6-bis(trihydroxysilyl)hexane).
Algae: EC50 (72 h): >100 mg/l; NOEC: ≥100 mg/l (nominal) (EC50 >74 mg/l when expressed in terms of concentration of the hydrolysis product, 1,6-bis(trihydroxysilyl)hexane).
An activated sludge respiration inhibition 3hr EC50value of >1000 mg/l (nominal) were determined in a reliable study.
The rapid hydrolysis of 1,6-bis(trimethoxysilyl)hexane (CAS 87135-01-1) (half-life 5.2 h at pH 7 and 25.1°C) means it is likely that the test organisms in each test were exposed primarily to the hydrolysis products, 1,6-bis(trihydroxysilyl)hexane and methanol.
No long-term toxicity data are available, however testing is not considered necessary and waiving is in place.
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