Registration Dossier
Registration Dossier
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EC number: 202-163-5 | CAS number: 92-52-4
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The reported 21-d NOEC of 0.17 mg/L for reproduction of Daphnia magna, as reported in the Key Study of Gersich et al. (1988) is used as key value in the aquatic hazard assessment.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.17 mg/L
Additional information
Two available studies are relevant to this information requirement, with only the study of Gersich et al. (1988) being suitably reliable for use in the chemical safety assessment. This study reports a 21-d flow-through reproduction toxicity test with Daphnia magna conducted in accordance with an in-house SOP of the Dow Chemical Company and GLP. The study reported a 21-d NOEC of 0.17 mg/L for both reproduction and mortality and will be used as a key study in the freshwater aquatic hazard assessment. The 21 -day NOEC value (reproduction) of 0.13 mg/L, reported by Ministry of Environment-Japan, is in good agreement with the Key Study. However, the reliability of this study cannot currently be assessed. No reliable studies were identified on saltwater species.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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