Registration Dossier
Registration Dossier
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EC number: 500-513-4 | CAS number: 161074-79-9 1 - 2.5 moles ethoxylated
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Justification for type of information:
- Please refer to the category justification provided in the category object.
Data source
Materials and methods
Test material
- Reference substance name:
- Alcohols, C12-13, branched and linear, ethoxylated, sulfates, sodium salts
- EC Number:
- 500-513-4
- EC Name:
- Alcohols, C12-13, branched and linear, ethoxylated, sulfates, sodium salts
- Cas Number:
- 161074-79-9
- Molecular formula:
- not applicable; UVCB
- IUPAC Name:
- Alcohols, C12-13, branched and linear, ethoxylated, sulfates, sodium salts
Constituent 1
Results and discussion
In vivo
Resultsopen allclose all
- Irritation parameter:
- erythema score
- Time point:
- 24/48/72 h
- Remarks on result:
- other: Irritating based on all available skin irritation data in the Alkyl Ether Sulfates (AES) category.
- Irritation parameter:
- edema score
- Time point:
- 24/48/72 h
- Remarks on result:
- other: Irritating based on all available skin irritation data in the Alkyl Ether Sulfates (AES) category.
Any other information on results incl. tables
For a detailed assessment of the skin irritation / corrosion potential of the Alkyl Ether Sulfates (AES) category, please refer to the category justification attached to the category object.
Applicant's summary and conclusion
- Interpretation of results:
- other: Skin irrit. 2, H315. Classification according to Regulation (EC) No. 1272/2008 (CLP/EU GHS).
- Conclusions:
- Applying read-across based on grouping of substances (category approach), an irritating potential is predicted for the target substance.
- Executive summary:
The available data on skin irritation / corrosion in the Alkyl Ether Sulfates (AES) category indicate a skin irritation potential for the target substance. As explained in the category justification, the differences in molecular structure and composition between the target substance and the members of the AES category are unlikely to lead to differences in the skin irritation / corrosion potential.
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