Registration Dossier
Registration Dossier
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EC number: 232-304-6 | CAS number: 8002-26-4 A complex combination of tall oil rosin and fatty acids derived from acidulation of crude tall oil soap and including that which is further refined. Contains at least 10% rosin.
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: The study was conducted according to OECD 117 test guideline, and in compliance with GLP.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Type:
- log Pow
- Partition coefficient:
- 4.9 - 7.7
- pH:
- 2
- Type:
- log Pow
- Partition coefficient:
- 3.2 - 6.8
- pH:
- 5 - 6
- Conclusions:
- A partition coefficient value of 4.9 - 7.7 at pH 2.0 and 3.2 - 6.8 at pH 5 - 6 for components of Tall Oil was determined in a reliable study conducted according to OECD 117, and in compliance with GLP.
Referenceopen allclose all
Description of key information
The study does not need to be conducted because the partition coefficient of a UVCB substance of this nature should be evaluated on the basis of the properties of its constituents. A result for the whole substance is not meaningful scientifically for the purpose of assessment of exposure or risk. It is therefore not appropriate to conduct or propose a test for this endpoint. The needs associated with a sound understanding of partition coefficient are adequately met by the available data on constituents. Reliable partition coefficient data are characterised by quantitative structure activity relationships (QSARs) for constituents of the substance.
Key value for chemical safety assessment
Additional information
In a supporting study conducted according to OECD 117, a partition coefficient of 4.9 - 7.7 and 3.2 - 6.8 at pH 2 and pH 5 - 6 was obtained for Distilled Tall Oil respectively.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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