Registration Dossier
Registration Dossier
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EC number: 202-613-0 | CAS number: 97-86-9
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
ECr50-72h = 44 mg/L, NOECr = 9.5 mg/L (Smyth and Long, 1999)
ECr50-72h = 16 mg/L, NOECr = 5.8 mg/L (Hoberg, 2002).
For the assessment the lowest value was used for 72 h - EC50 and NOEC.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 16 mg/L
- EC10 or NOEC for freshwater algae:
- 5.8 mg/L
Additional information
Data availability
There are two reliable studies available for i-BMA. For the assessment the lowest value was used for 72 h - EC50 and NOEC, as recommended by the guidance (CLP criteria 4.1.3.2.4.3).
Discussion
Two studies on Pseudokirchneriella subcapitata have been conducted according to OECD Guideline 201. The studies were performed in closed vessels and included test substance analysis. The relevant toxicity values are ECr50-72h = 44 mg/L, NOECr = 9.5 mg/L (Smyth and Long, 1999) and for the other study ECr50-72h = 16 mg/L, NOECr = 5.8 mg/L (Hoberg, 2002).
An investigation with a series of 12 marine species (fish, invertebrates, several algae) gave no indication of a higher sensitivity of marine species. To the contrary, LC/EC50 values and NOECs tended to be higher than the corresponding freshwater data.
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