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Toxicological information

Direct observations: clinical cases, poisoning incidents and other

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Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Type of information:
other: Review
Adequacy of study:
supporting study
Reliability:
other: Review

Data source

Reference
Reference Type:
review article or handbook
Title:
Hydrazin, Hydrahzinhydrat und Hydrazinsulfat, BUA Stoffbericht No. 205
Author:
BUA (Beratergremium umweltrelevanter Altstoffe)
Year:
1996
Bibliographic source:
S. Hirzel Wissenschaftliche Verlagsgesellschaft

Materials and methods

Study type:
poisoning incident
Endpoint addressed:
acute toxicity: oral
Principles of method if other than guideline:
poisoning incidents

Test material

Constituent 1
Chemical structure
Reference substance name:
Hydrazine
EC Number:
206-114-9
EC Name:
Hydrazine
Cas Number:
302-01-2
Molecular formula:
H4N2
IUPAC Name:
hydrazine
Details on test material:
no further data

Method

Type of population:
occupational
Subjects:
poisoning incidents
Ethical approval:
not applicable
Route of exposure:
other: different routes
Reason of exposure:
accidental
Exposure assessment:
not specified
Examinations:
poisoning incidents
Medical treatment:
no data

Results and discussion

Clinical signs:
acute poisoning : vomiting, depression of central nervous system, liver and kidney damage and after inhaltaion pulmonary edema
Results of examinations:
A clear correlation between symptoms and exposure level is not given:
Effectivity of medical treatment:
no data
Outcome of incidence:
In man, acute poisoning with hydrazine causes vomiting, depression of central nervous system, liver and kidney damage and after inhaltaion pulmonary edema.

Applicant's summary and conclusion