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EC number: 232-033-3 | CAS number: 7783-90-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
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- Additional physico-chemical information
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- Endpoint summary
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- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
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- Additional toxicological data

Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The NOEC for inhibition of nitrification is 0.025 mg Ag/L.
Key value for chemical safety assessment
Additional information
The PNECmicroorganisms is intended to protect the degradation functions and process performance and efficiency of domestic and industrial sewage treatment plants (STP). ECHA guidance (ECHA 2008) allows the derivation of a PNECmicroorganisms from a wide range of laboratory tests utilising microorganisms, including standardised biodegradation tests, respiration inhibition tests, activated sludge growth inhibition tests, pilot scale activated sludge simulation tests and tests performed with specific bacterial populations, such as nitrifying bacteria or ciliates. Data on the toxicity of silver in Microtox assays (e.g. Hsieh et al. 2004) are not considered relevant to STP functioning. Nitrifying bacteria are considered to be the most sensitive component of the microbial fauna found in STP and tests investigating effects on these fauna are preferred to more generic microbial testing when deriving a PNECmicroorganisms. An AF of 1 is applied to NOECs from these types of tests when deriving a PNECmicroorganisms (the AF for other microbial tests range from 10 – 100).
Two studies (Choi et al. 2008a,b) report the effects of ionic silver on nitrification inhibition. Additional methodological information was obtained for both of these studies from Hu et al. (2002). Both studies used a population of nitrifying bacteria initially obtained from a municipal STP (Missouri, USA) and each reports inhibition of nitrification of between 10 and 20% at the lowest test concentration (LOEC) of silver tested. Where a LOEC is associated with effects >10% but <20% ECHA guidance (ECHA 2008) allows a NOEC to be calculated as LOEC/2. This results in NOECs of 0.025 and 0.05 mg Ag/L for Choi et al (2008a) and Choi et al. (2008b), respectively.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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