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Ecotoxicological information

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Data are available for short-term toxicity of the registered substance to fish, aquatic invertebrates and algae.

A 96 hours LC50 value of 597 mg/l has been determined for effects on mortality of Danio rerio.

A 48-h EC50 value of 81 mg/l has been determined for effects on mobility of Daphnia magna.

A 96-hour EC50 value of 8.8 mg/l and NOEC of 3.1 mg/l have been determined for effects on growth rate of Pseudokirchneriella subcapitata.

A 21-day NOEC of ≥1 ppm (≥1 mg/l) has been determined for the effects of the test substance on survival and reproduction of Daphnia magna in a long-term test.

A data waiver is applicable for long-term toxicity to fish.

The aquatic toxicity studies were conducted at pH 8 and above in many cases. The neutral form of the amine, i.e. the un-ionised form, is more toxic than the ionised form. This pattern of toxicity is consistent with ammonia, where the un-ionised form, NH3, is more toxic than the ionised form, NH4. The difference in toxicity is due to bioavailability, where the un-ionised form can cross cell membranes more readily than the ionised form. Therefore, for waters having a pH closer to 7 it is likely that the study results overestimate the toxicity of the registered substance.