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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
other: reliability not verifiable
Rationale for reliability incl. deficiencies:
other: no detailed information in SNIF#001-4.1.11-01

Data source

Reference
Reference Type:
other: No information provided
Title:
Unnamed
Year:
1987

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 401 (Acute Oral Toxicity)
GLP compliance:
yes
Limit test:
yes

Test material

Test animals

Species:
rat
Strain:
Wistar
Sex:
male/female

Administration / exposure

Vehicle:
polyethylene glycol
Remarks:
400
Doses:
5000 mg / kg bw
No. of animals per sex per dose:
5 males
5 females

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 5 000 mg/kg bw
Based on:
test mat.
Clinical signs:
Unspecific intoxication symptoms reversible within 3 days (red colouration of the limps).
Gross pathology:
No morphological changes observed at the post mortem examination.

Any other information on results incl. tables

 sex  dose (mg / kg bw)  number of animals number of deaths 
 M  5000  5  0
 F  5000  5  0

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
Not subject to classification and labelling