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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

The toxicity of OTNE towards the early life stages of Danio rerio was investigated according to international guidelines (OPPTS 85.1400 / OECD Guideline 210) under GLP. Fish were exposed to 14C-labeled OTNE in a flow-through test (semi-static until day 4 after all eggs had hatched) at nominal concentrations of 0.02, 0.05, 0.2, 0.4 and 0.8 mg/l. Validity criteria for the test were met. The 30d-NOECs based on mean measured concentrations for egg survival, hatching time, post hatch survival and body weight and length were found to be 0.54, 0.54, 0.30 and 0.16 mg/l respectively. The 30d-LOEC and 30d-LC50 for body weight and length were found to be 0.29 and >0.30 mg/l respectively (also based on mean measured concentrations).

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
0.16 mg/L

Additional information