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Physical & Chemical properties

Partition coefficient

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Description of key information

According to the OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method) a logPow of 5 was determined for N-(1,3-benzothiazol-2-ylsulfanyl)cyclohexanamine at pH 7 and 25°C (Currenta, 2010).

Key value for chemical safety assessment

at the temperature of:
20 °C

Additional information

5 mins shaking used in the test of Monsanto (1980) is too short to support sufficient equilibration. However longer equilibration time is not prefered either because CBS is considered as unstable in water with a hydrolysis half-life of 12.5 hours and 100% hydrolyzation in 24.9 hours (Monsanto, 1984). Therefore shaking method is not a suitable system to test the partitioning coefficient of CBS. The determined logPow of 5 (OECD Guideline 117, HPLC method) is used instead as key study (Currenta 2010).