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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

The acute toxicity of kieselguhr soda ash flux calcined  to Daphnia magna was investigated in a GLP study performed in accordance with OECD Guideline 202. The 48 h EC50 was >100% v/v saturated solution and the NOEC was 100% v/v saturated solution.

Key value for chemical safety assessment

Additional information

The key study (Priestly 2010) was performed to OECD Guideline 202 and in accordance with GLP. The study assessed the acute toxicity to Daphnia magna in a limit test. Pre-study solubility work indicated that a solution of the test item could not be attained using conventional methods, for example, ultrasonication or high shear mixing. Given the insoluble nature of the test item and also its high purity value, it was considered that the most suitable method of preparation was as a saturated solution.

Following a preliminary range-finding test, twenty daphnids (4 replicates of 5 animals) were exposed to an aqueous solution of the test item at a concentration of 100 % v/v saturated solution for 48 hours. Immobilisation and any adverse reactions to exposure were recorded after 24 and 48 hours. The 48-Hour EC50for the test item to Daphnia magna based on nominal test concentrations was greater than 100 % v/v saturated solution and correspondingly the No Observed Effect Concentration was 100 % v/v saturated solution.