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Diss Factsheets
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EC number: 203-049-8 | CAS number: 102-71-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
The biodegradation of 2,2',2''-nitrilotriethanol (TEA) was best examined by West & Gonsior (1996). Tests were conducted with 14C-labelled TEA regarding the biodegradation in soil, river water and river water-sediment systems as well as the activated sludge reaction. In a water-sediment microcosm-study with natural sediment and water samples a maximum biodegradation half-life of 0.6 days and a maximum mineralization half-life of 7.2 days was found.
In a river-water microcosm-study with natural river water samples a maximum biodegradation half-life of 1.7 days and a maximum mineralization half-life of 1.9 days was found.
Depending on the initial test substance concentration under semi-realistic conditions with soil microcosms using natural sandy loam soil a maximum biodegradation half-life of 1.8 days and a maximum mineralization half-life of 5.4 days were determined.
In a test with activated sludge biodegradation half-lifes between 0.01 and 0.51 days and mineralization half-lifes between 0.24 and 0.67 days were found, depending on the initial concentration of the test substance (164 and 818 mg/L) and the concentration of the activated sludge (0.6 and 5.7 mg/L MLSS).
These results indicate, that2,2’,2’’-nitrilotriethanol is readily biodegradable. A ready test performed by Gerike (1978) according to a precursor of the Modified OECD Screeening Test (OECD TG 301 E) using non-adapted effluent from a waste water treatment plant as inoculum supports these results.
In the Guidance on the application of CLP criteria, a substance can be identified as rapidly biodegradable if the measured rate constant in the different environmental compartments is > 0.043 d-1 (Guidance on the application of CLP criteria, Guidance to regulation (EC) No 1272/2008 on classification, labelling and packaging (CLP) of substances and mixtures, ANNEX II, 2.3). The measured rate constant for biodegradation and mineralization are all > 0.043 d-1. Therefore, according to CLP criteria, TEA is rapidly biodegradable. These results also lead to the conclusion, that TEA is readily biodegradable. Hence, TEA degrades rapidly in the environmental compartments water, sediment and soil.
While the substance is readily biodegradable in freshwater system, it is not readily biodegradable in marine systems (Eide-Haugmo et al., 2009/2012).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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