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EC number: 212-819-2 | CAS number: 872-05-9
The test material was classified as non-irritating because the group mean was 0 for both erythema and oedema at 24, 48, and 72 hours.
In a primary dermal irritation study, young adultwhite rabbits (3/sex) were dermally exposed to 0.5 millilitres of 1-hexene, 99.4% pure, for 4 hours to 2 centimetres x 2 centimetres of body surface area. Animals then were observed for 7 days. Irritation was scored based on OECD guidelines, on a scale of 0 to 4.
The application of 1 -hexene resulted in no skin reactions, with a mean irritation score of 0 for erythema and oedema at all time points.In this study, 1-hexene is not a dermal irritant.
This study received a Klimisch score of 1and is classified asreliable without restriction, because the study was carried out closely following OECD Guideline 404 and was GLP compliant.
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