Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Acute data with varying reliabilities (Klimisch rating), based on international or national guidelines, are available for three trophic levels: Algae, Invertebrates, Fish and Microorganisms. These data are summarised in the table below:

Level of exposure / trophic levels

Organism

EC50/LC50

NOEC

Flag / reliability

Performing laboratory

Reference in IUCLID

Acute / Aquatic algae

Scenedesmus subspicatus

72h: 22 mg/L (growth rate)

72h: 6.8 mg/L (biomass)

K/2

Hüls

Toxicity to aquatic algae and cyanobacteria, Scholz, 1997, RS, K

Acute / Aquatic invertebrates

Daphnia magna

48h: 5.3 mg/L

48h: Not determined

K/2

Unilever Research

Short-term toxicity to aquatic invertebrates, Marshall, 1994, RS, K

Acute / Aquatic invertebrates

Daphnia magna

24h: 7 mg/L

24h: Not determined

S/2

Hüls

Short-term toxicity to aquatic invertebrates, Scholz, 1995, SS, S

Acute / Fish

Cyprinus carpio

96h: 8.6 mg/L

96h: Not determined

K/1

Hüls

Short-term toxicity to fish, Scholz, 1997, RS, K

Acute / Fish

Leuciscus idus melanotus

48h: 15 mg/L

48h: Not determined

S/4

Hüls

Short-term toxicity to fish, Scholz, 1996, SS, S

Acute / Micro-organisms

activated sludge

3h: 302 mg/L

3h: 122 mg/L

K/1

Hüls

Toxicity to microorganisms, Diefenbach, 1997, RS, K

Acute / Microorganisms

Pseudomonas putida

6h: Not determined

6h: 1.15 mL/L

S/2

Hüls

Toxicity to microorganisms, Diefenbach, 1996, SS, S

Among all data available, the aquatic invertebrate,Daphnia magna,is the most sensitive species with a 48h-EC50 at 5.3 mg/L.For algae and fish, the L(E)C50 values were determined at 22 mg/L (based on growth rate) and 8.6 mg/L, respectively.For microorganisms, the 3h-EC50 and 3h-EC10 values were determined at 302 mg/L and 122 mg/L respectively.

In accordance with column 2 of REACH annex IX, further testing on the long-term effects on aquatic organisms does not need to be conducted as the chemical safety assessment does not indicate a need for further investigation.

Additional information