Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

Toxicological testing was performed with UGI Exxaro sulphate slag, since this test material was chosen as representative material based on particle size distribution (smallest particle size as reported under 4.5 particle size distribution - k_Weidenfeller_2007) and on in vitro bioavailablity/bioaccessibility testing (highest bioelution pattern as reported under 7.1.1 basic toxicokinetics).

Migrated from Short description of key information:
Skin sensitisation was tested in a guinea pig maximisation test according to Magnusson and Kligman.

Justification for classification or non-classification


The reference Leuschner (2008) is considered as the key studies on skin sensitisation and will be used for classification. The overall sensitisation results of a skin sensitisation test in guinea pigs according to Magnusson and Kligman (maximisation test) are as follows:

Under the present test conditions UGI revealed no sensitising properties in guinea pigs in a test model according to Magnusson and Kligman. Thus, the classification criteria acc. to regulation (EC) 1272/2008 as skin sensitizer are not met.


Respiratory sensitisation:

There is no evidence on specific respiratory hypersensitivity in humans following repeated inhalation exposure with UGI. Thus, the classification criteria acc. to regulation (EC) 1272/2008 as respiratory sensitiser are not met.