Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 200-313-4 | CAS number: 57-11-4
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 for invertebrates: no effects within water solubility
Key value for chemical safety assessment
Additional information
Hooftman (1991) presented a GLP study with Daphnia magna conducted according to EU method C.2 under static conditions for 47h. Tertiary buty alcohol was used as vehicle. No toxicty of stearic acid was observed at the highest nominal concentration tested. The EC50 is therefore >32 mg/L.
The publication from Curtis (1970) with Artemia salina in saltwater resulted an LC50 of >20 mg/L for stearic acid. However, only limited data is provided and the study was rated reliability 4.
Since the results from the above mentioned studies are either obtained by using a vehicle or based on insufficient information, in addition read across is done to the shorter-chain fatty acid palmitic acid (C16), which is a member of the fatty acids category, and a weight of evidence approach is applied. This limit test with Daphnia magna was provided by the Ministry of the Environment, Government of Japan conducted by a not named author (2000). The study was conducted with 98.7% pure palmitic acid according to the "Circular on Japanese Test Methods of new chemical substances, Daphnia acute toxicity test" according to GLP. In this static test the EC50 (48h) was found to be >4.8 mg/L.
The read across to palmitic acid (C16) supports the results by Hooftman (1991) and Curtis (1970), in that there is no short-term toxicity to aquatic invertebrates by stearic acid within the water solubility of 0.597 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
