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Type of information:
other: statistical review
Adequacy of study:
weight of evidence
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Statistical approach to available data, however, no attempt was made weight individual reported densities for quality.
no guideline followed
Principles of method if other than guideline:
The mean density was calculated for multiple measurements reported in the literature.
GLP compliance:
Type of method:
other: statistical review
0.945 g/cm³
25 °C
Remarks on result:
other: 95%C.I. 0.94498 – 0.94574g/cm3
The mean literature density for cyclohexanol is 0.94536 g/cm3 (0.94498 – 0.94574g/cm3) at 25°C.In addition to experimental uncertainty in the density measurement, the above statistical value can be expected to encompass variation due to sample purity. Bias introduced by data recycling cannot be excluded, but has been attempted to be controlled for, although without inspection of every reference.

Description of key information

0.94536 g/cm3 (0.94498 – 0.94574 g/cm3) at 25 °C, mean literature value, n=9
0.94496 g/cm3, 25 °C, oscillating tube densimeter, Hovorka 1999

Key value for chemical safety assessment

Relative density at 20C:

Additional information

A survey of available literature data was carried out for the density of cyclohexanol in the liquid state (25 °C), rather than at the standard 20 °C. The potential data sources were restricted to two bibliographic databases, augmented by data from other studies previously identified. No attempt was made to weight individual studies by reliability, instead a statistical approach was taken. Data from obvious secondary sources, and multiple reports of a numerically equivalent density by the same authors, were discarded as potential sources of bias due to data recycling. Data points lying outside two standard deviations, most likely resulting from impurities, unreported or misreported experimental conditions, or bibliographic indexing mistakes, were treated as outliers and discarded.

One reference was explored in further detail, and found to be of sufficient quality for use as a standalone study (Hovorka 1999).

The mean value is taken forward for the purposes of risk assessment, as being most representative of the commercial substance. The available data is considered to be relevant, reliable, and adequate for risk assessment purposes. The endpoint is complete, in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.1.1.