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Physical & Chemical properties

Partition coefficient

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
GLP compliance:
no
Type of method:
flask method
Partition coefficient type:
octanol-water
Analytical method:
gas chromatography
Key result
Type:
log Pow
Partition coefficient:
1.25
Temp.:
25 °C
pH:
7

Evaluation of isolated components: Cyclohexanol

log Pow = 1.25

Study was performed without adjustment of pH value.

Conclusions:
The log Kow of cyclohexanol was determined with the shake flask method and found to be 1.25.
Executive summary:

The octanol-water partition coefficient of cyclohexanol was determined with the shake flask method under non-GLP conditions in accordance with OECD Testing Guideline 107. The log Kow was found to be 1.25.

Description of key information

1.25 at 25 °C, OECD 107, BASF (1988)

Key value for chemical safety assessment

Log Kow (Log Pow):
1.25
at the temperature of:
25 °C

Additional information

The available study on Partition Coefficient is relevant, adequate and reliable with restrictions (Klimisch 2) and its result is considered for the purpose of classification and labelling and risk assessment.

Hansch (1967) was the recommended value suggested by the LOGKOW Databank (Sangster) and it is reported as supporting data.