Registration Dossier

Administrative data

Endpoint:
additional ecotoxicological information
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
significant methodological deficiencies

Data source

Reference
Reference Type:
publication
Title:
Influence of alcohols and potassium salts of xanthogenic acids on various biological objects
Author:
Chvapil M, Zahradnik R, Cmuchalova B
Year:
1962
Bibliographic source:
Arch. Int. Pharmacodyn. 135, 330-343

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
The inhibition of the movement of the worm Tubifex tubifex was studied by immersing 10 worms per test concentration into an aqueous solution of yclohexanol at a temperature of 20 °C. The concentration of cyclohexanol at which the movement of all worms was inhibited within 120 seconds was determined.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Applicant's summary and conclusion

Conclusions:
The movement of the worm Tubifex tubifex was inhibited within 120 seconds at a concentration of 4800 mg/L in this experiment.
Executive summary:

A non-guideline, non-GLP study was conducted to study the effect of cyclohexanol on the worm Tubifex tubifex. Per experiments, ten worms were immersed in an aqueous solution of cyclohexanol and the inhibition of the worms over a period of 120 seconds was studied. At the concentration of 4800 mg/L, the movement of all worms was inhibited within 2 minutes.