Registration Dossier
Registration Dossier
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EC number: 201-178-4 | CAS number: 79-11-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Explosiveness
Administrative data
Link to relevant study record(s)
- Endpoint:
- explosiveness, other
- Study period:
- 11 May 2009 - 4 November 2009
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.14 (Explosive properties)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Interpretation of results:
- Division 1.4 (substances, mixtures and articles which present no significant hazard) based on GHS criteria
- Remarks:
- Migrated information
- Conclusions:
- In conclusion, Monochloroacetic acid (MCAA) is not explosive.
Reference
The tendency of a compound to undergo violent or explosive decomposition is an important safety consideration. In general, the oxygen balance and various structural parameters (bond groupings) are factors associated with explosive properties.
The molecular structure of the test substance does not contain any chemically instable or highly energetic groups that might lead to an explosion. The impurities, present for < 0.3% in the test substance, were not taken into account but it is not to be expected that these have any influence.
The oxygen balance of a compound is the difference between the oxygen content of the compound and that required to fully oxidize the carbon, hydrogen and other oxidisable elements to carbon dioxide, water, etc. Nitrogen is not considered oxidisable and is usually liberated as the gaseous element during explosive decomposition.
The oxygen balance is calculated for the chemical reaction:
CcHhOo + [c + (h/4) – (o/2)] O2→c CO2+ (h/2) H2O
where c, h and o are the amounts of carbon, hydrogen and oxygen atoms respectively.
Oxygen balance (%) = -1600 x [2 x c + (h/2) – o] / molecular weight
If there is a deficiency of oxygen, the balance is negative, while an excess of oxygen gives a positive balance. Compounds with a positive balance can act as oxidants and are often explosive in nature. However, there are known explosives with an oxygen balance of - 64%. Compounds with an oxygen balance which is more negative than -200% are not considered to pose an explosive risk.
Using C2H3O2Cl as molecular formula and 94.497 g/mol as molecular weight, the oxygen balance for the test substance was calculated to be –59 %. This is > -200% and therefore within the region where there may be a potential for explodability. However, there are no plosophores (bond groupings known to give explosive properties) or auxoploses (explosive enhancing groups) present in the structure. The relatively high oxygen balance is considered to be due to the size of the molecule in combination with the presence of a chlorine atom and a carboxylic acid group in the molecule. Overall consideration of the properties does not suggest a risk of explodability.
Description of key information
Based on structure, Monochloroacetic acid (MCAA) is not explosive.
Key value for chemical safety assessment
- Explosiveness:
- non explosive
Additional information
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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