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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to birds

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
long-term toxicity to birds: reproduction test
Data waiving:
other justification
Justification for data waiving:
other:

Description of key information

For reasons of animal welfare, no study on toxicity to birds is performed. Mammalian toxicity data are considered in detail for human health protection and showed no hint for adverse effects. Therefore, and due to the non bioaccumulative potential of MDA no toxicity to birds is expected either

Key value for chemical safety assessment

Additional information

For reasons of animal welfare, no study on toxicity to birds is performed. Mammalian toxicity data are considered in detail for human health protection and showed no hint for adverse effects. Therefore, and due to the non bioaccumulative potential of MDA no toxicity to birds is expected either. Furthermore, an exposure is unlikely since MDA is used only under strictly controlled conditions.


In a publication of Schafer et al. 1983 an experimental study on the redwinged blackbird (Agelaius phoenniceus) showed no toxic effects after exposure via the feed over 18 h and an LC50 > 148 mg/kg. Due to missing detailed information, the study was rated as not reliable. Therefore, the determined LC50 is not used but the study confirms the assumption of from the other mammalian data, that MDA is not toxic to mammals and birds.