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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

No toxic effects on microorganisms were observed up to the limit of water solubility, no PNEC is derived. 

Key value for chemical safety assessment

Additional information

Within the fatty acid category studies describing the toxicity of fatty acids to Pseudomonas putida are available. For palmitic acid C16 (CAS 57 -10 -3) one test is available which is conducted according to DIN 38472 Part 27 (Kirch 1994). In this test an EC10 > 3000 mg/L is reported after 30 min exposure based on respiration rate. Though this test does not meet the requirements of todays standard procedures, the results are considered reliable to demonstrate the low toxicity of the test substance. Nevertheless, in addition, read-across is performed to a study conducted with stearic acid C18 (CAS 57 -11 -4). For this substance a cell multiplication inhibition test was conducted following GLP-requirements. The used method in the test was similar to the ISO guideline 10712. In the study an EC10 (18 h) of 883 mg/L (nominal) (Coenen, 1989) was reported. Concluding from the results of both studies palmitic acid is regarded to be not toxic to microorganisms. As no toxic effects on microorganisms were observed up to the limit of water solubililty, no PNEC is derived.