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Short-term toxicity to fish

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Description of key information

Two short-term acute tests ulilizing two different speices resulted in no observable effect concentrations that were well above the water solubility of the test substance.

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Additional information

Short-term (acute) toxicity to fish was evaluated in two studies with two different species.  In both studies the no observable effect concentrations were well above the solubility of the test substance. A pre- GLP 96-h acute toxicity was conducted utilizing fathead minnows (P. promelas). The organisms were exposed at nominal concentrations of 0, 98.4, and 984 mg/L under static conditions.  There was no mortality or abnormal effects observed at 984 mg/L (1000 uL/L), the highest exposure concentration during this study. The 96 -h NOEC value was ≥ 984 mg/L.  A second study under GLP was conducted with Rainbow trout (O. mykiss). In that 7-day acute toxicity study, the organisms were exposed at measured concentrations of 0, 0.013, 0.021, 0.038, 0.080, and 0.25 mg/L under flow-through conditions. There was no mortality or abnormal effects observed at any of the exposure concentrations during this study.  The 7-day NOEC value was 0.25 mg/L, the highest concentration tested.