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EC number: 700-206-7 | CAS number: -
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The 72 h ErC50 and EbC50 of the test material to Desmodesmus subspicatus were estimated to be 55 mg/L and 8.4 mg/L, respectively, based on read-across to results obtained for a comparable substance.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 55 mg/L
- EC10 or NOEC for freshwater algae:
- 1 mg/L
Additional information
Synthetic inositol phosphates are composed of a mix of inositol phosphates (25.0 – 38.4%) and orthophosphoric acid (23.8 – 26%) in water. The toxicity to algae of this substance can therefore be determined based on data for these two components :
- Inositol phosphates: A study conducted on the test material (‘Inositol phosphates from rice bran’) containing a comparable amount of inositol phosphates (26.8 - 29.1%) but less orthophosphoric acid (0.4 – 1%) yielded a 72 h ErC50 for Desmodesmus subspicatus equivalent to 55 mg/L(based on nominal concentrations). Read-across between the two substances is considered possible as their inositol phosphate content and physico-chemical properties (e.g. water solubility, log Kow, melting/freezing point, boiling point, relative density and surface tension) are in comparable ranges.
- Orthophosphoric acid: Toxicity to algae from orthophosphoric acid is not expected. Indeed, orthophosphoric acid is a source of phosphate, a nutrient that is essential to algae growth. In large concentrations, phosphate causes excessive growth of algae rather than toxicity. Also, the presence of orthophosphoric acid does not significantly decrease the pH of the substance compared to ‘Inositol phosphate from rice bran’, as both have a pH below 1 in undiluted form. No specific pH-related toxicity will therefore occur.
In conclusion, the toxicity to algae of ‘Synthetic inositol phosphate’ is expected to be comparable to that of ‘Inositol phosphates from rice bran’, with a 72 h ErC50 = ca. 55 mg/L.
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