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EC number: 271-030-1 | CAS number: 68514-28-3
Pathological examination 2000 mg/kg males
Without pathologic changes, (viscous content of intestine)
Pathological examination 2000 mg/kg females
The test was performed according to the Method B.3 Acute Toxicity (Dermal), Directive 92/69/EEC, published in OJ L 383A, 1992.
The test substance was tested for the assessment of acute dermal toxicity using Wistar rats.
The study was performed as limit test: two groups of animals - 5 males and 5 females and the dose of 2000 mg/kg. The test substance was applied on the shaved skin of the test animals in delivered form (moistened with the smallest amount of water) for 24 hours.
The test animals were observed 14 days after application, afterwards were sacrificed and the necropsy for macroscopic examination of the organs was performed.
The test substance applied in dose 2000 mg/kg did not cause the death of animals. No clinical signs of toxicity were observed during the study in all animals. Macroscopic changes were diagnosed during pathological examination in two animals (lungs – dark red punctiform strata).
According to the results of study the value of LD50 dermal of the test substance for rats of both sexes is higher than 2000 mg/kg.
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