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EC number: 219-785-8 | CAS number: 2530-85-0
Table 1. Test results
*A negative value indicates that growth rate or biomass was higher in the treated media than in the Control.
WoE Short-term toxicity to algae: 72 hr ErC50 >100 mg/l and NOEC of =100 mg/l (measured, highest concentration tested) according to EU C.2 (CAS 2530-85-0, Momentive 2002)
WoE Short-term toxicity to algae: 72 hr ErC50 >536 mg/l and NOEC of 322 mg/l (measured, highest concentration tested) according to EU C.2 (CAS 2530-85-0, Evonik 2000)
The observations in these study are attributed to the exposure of test organisms to the hydrolysis products in the test system.
A 72-h EC50 value of >100 mg/l and NOEC of =100 mg/l (measured, highest concentration tested) have been determined for the effects of the test substance (CAS 2530-85-0) on growth rate of Scenedesmus subspicatus. Test media were prepared by direct addition with stirring for 35 minutes. However in view of the exposure period it is likely that the test organisms were primarily exposed to the hydrolysis products of the substance (Momentive 2002).
In a second reliable test, a 72-h EC50 value of >536 mg/l and NOEC of 322 mg/L were determined. In this test, the registration substance would have been fully hydrolysed during preparation of stock solution (which was also filtered prior to the exposure period) (Evonik 2000). There is potential for oligomerisation to have occurred during preparation of the stock, however, high recoveries at the end of the test indicate that precipitation did not occur to a significant extent. At the loading levels corresponding to the NOEC and EC50 the concentration of monomeric silanol should have been stable in the test medium.
Both of these reliable studies provide useful weight of evidence for the hazard assessment.
Refer to the discussion in the Section 6 endpoint summary (Section 7.0 of CSR) for further discussion of the approach to chemical safety assessment for the registered substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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