Registration Dossier
Registration Dossier
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EC number: 229-722-6 | CAS number: 6683-19-8
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
No experimental data on hydrolysis is available. However, the substance has ester bonds which could be subject to slow hydrolysis.
Key value for chemical safety assessment
Additional information
The estimations of hydrolysis (HYDROWIN v 2.0) show very slow DT50’s, greater than 2 years and greater than70 days at pH 7 and 8, respectively.
The potential degradation products are “Metilox acid” (CAS 20170-32-5), and pentaerythritol (CAS 115-77-5) (PBT-Assessment No. 77 for the test substance by the European Commission Joint Research Centre).
Considering the high adsorption potential and the low water solubility, the extend of hydrolysis is expected to be low.
QSAR-disclaimer
In Article 13 of Regulation (EC) No 1907/2006, it is laid down that information on intrinsic properties of substances may be generated by means other than tests, provided that the conditions set out in Annex XI (of the same Regulation) are met.
According to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can be used if (1) the scientific validity of the (Q)SAR model has been established, (2) the substance falls within the applicability domain of the (Q)SAR model, (3) the results are adequate for the purpose of classification and labeling and/or risk assessment and (4) adequate and reliable documentation of the applied method is provided.
For the assessment of CAS 6683-19-8 (Q)SAR results were used for hydrolysis. The criteria listed in Annex XI of Regulation (EC) No 1907/2006 are considered to be adequately fulfilled and therefore the endpoint(s) sufficiently covered and suitable for risk assessment.
Therefore, further experimental studies on hydrolysis are not provided.
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