Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
Value:
2 720 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Dose descriptor:
LC50
Value:
5 810 mg/m³ air

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
LD50
Value:
28 269.15 mg/kg bw

Additional information

Based on the experimental results obtained (reported under the endpoint record 07.02.01_05 KAc) with the analogue Potassium Acetate (LD 50 for male rats = 3.25 (2.48-4.26) g/kg) and the molecular weights, the read-across approach is applied and the LD50 for substance Sodium Acetate is calculated to be 2.72 (2.07-3.56) g/kg bw.

Based on the experimental results (reported under the endpoint record 07.02.02_02 CaAc) obtained with the analogue Calcium Acetate (LC 50 for female rats > 5.6 mg/L air) and the molecular weights, the read-across approach is applied and the LC50 for substance Sodium Acetate is calculated to be higher than 5.81 mg/L air under test conditions.

Based on the experimental results (reported under the endpoint record 07.02.03_02 Fumaric Acid) obtained with the analogue Fumaric Acid (LD 50 for New Zealand rabbits > 20000 mg/kg bw) and the molecular weights, the read-across approach is applied and the LD 50 for substance Sodium Acetate is calculated to be greater than 28269.15 mg/kg bw under test conditions.

Justification for classification or non-classification

Acute toxicity:

Oral: LC50>2000mg/kg bw: non- classification

Dermal: LC50>2000mg/kg bw: non- classification

Inhalation: LC50>5 mg/L: non-classification