Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 931-334-3 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Sediment toxicity
Administrative data
- Endpoint:
- sediment toxicity: short-term
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
- Justification for type of information:
- As the test substance does not dissolve in water, the mechanism of partitioning from the water phase and thus uptake by diffusion from the water phase does not take place. Thus exposure of sediment organisms to the test substance may occur only by oral intake of solid particles of the test substance. An effect in the organism would then be caused by internal partitioning of test substance (as modelled by equilibrium partitioning and for highly lipophilic substance with an additional factor of 10, see Guidance Document on Information Requirements and Chemical Safety Assessment R.10 and R.16). However, for activated carbon no absorption is expected (see toxicokinetic assessment). The absence of effects from oral intake of activated carbon is supported by the results of an acute toxicity study with rats where no adverse effects were observed after oral exposure to 2000 mg/kg (C80453). Thus there seems to be no justification in testing the effects of oral exposure of soil and sediment organisms. This is confirmed by the results of the reproduction toxicity test with earthworms (OECD 222), read across from Activated Carbon - High Density Skeleton, in which the NOEC was observed to be 1000 mg/kg soil. Therefore further testing with sediment organisms is waived
Data source
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 850.1790 (Chironomid Sediment Toxicity Test)
- Deviations:
- no
Results and discussion
Applicant's summary and conclusion
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