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Toxicological information

Acute Toxicity: dermal

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Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
disregarded due to major methodological deficiencies
Study period:
Not Reported
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original reference not available
Cross-referenceopen allclose all
Reason / purpose:
reference to same study
Reason / purpose:
reference to other study

Data source

Reference
Reference Type:
review article or handbook
Title:
Nickel (II) hydroxide
Author:
NIOSH
Year:
2008
Bibliographic source:
In: Registry of Toxic Effects of Chemical Substances #QR7040000

Materials and methods

Principles of method if other than guideline:
Not Reported
GLP compliance:
not specified
Test type:
other: no data

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Not Reported
- Name of test material (as cited in study report): Nickel (II) hydroxide

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified
Details on test animals and environmental conditions:
Not Reported

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified
Details on dermal exposure:
Not Reported
Duration of exposure:
Not Reported
Doses:
Effect levles based on >2 g/kg; doses not reported
No. of animals per sex per dose:
Not Reported
Control animals:
not specified
Details on study design:
Not Reported
Statistics:
Not Reported

Results and discussion

Preliminary study:
Not Applicable
Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 2 other: g/kg
Mortality:
Not Reported
Clinical signs:
Not Reported
Body weight:
Not Reported
Gross pathology:
Not Reported
Other findings:
Not Reported

Any other information on results incl. tables

Not Applicable

Applicant's summary and conclusion

Interpretation of results:
other: no data
Remarks:
Criteria used for interpretation of results: other: no data
Conclusions:
lethal dose (50 percent kill): >2g/kg
Executive summary:

Study rated by an independent reviewer.