Registration Dossier

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
disregarded due to major methodological deficiencies
Study period:
Not Reported
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original reference not available
Cross-referenceopen allclose all
Reason / purpose:
reference to same study
Reason / purpose:
reference to other study

Data source

Reference
Reference Type:
review article or handbook
Title:
Nickel (II) hydroxide
Author:
NIOSH
Year:
2008
Bibliographic source:
In: Registry of Toxic Effects of Chemical Substances #QR7040000

Materials and methods

Principles of method if other than guideline:
Not Reported
GLP compliance:
not specified
Limit test:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Not Reported
- Name of test material (as cited in study report): Nickel (II) hydroxide

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified
Details on test animals and environmental conditions:
Not Reported

Administration / exposure

Route of administration:
subcutaneous
Vehicle:
not specified
Details on exposure:
Not Reported
Doses:
50 mg/kg (other doses not reported)
No. of animals per sex per dose:
Not Reported
Control animals:
not specified
Details on study design:
Not Reported
Statistics:
Not Reported

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LC50
Effect level:
50 mg/kg bw
Mortality:
Not Reported
Clinical signs:
Not Reported
Body weight:
Not Reported
Gross pathology:
Not Reported
Other findings:
Not Reported

Any other information on results incl. tables

Not Applicable

Applicant's summary and conclusion

Conclusions:
Not Reported
Executive summary:

Study rated by an independent reviewer.