Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
disregarded due to major methodological deficiencies
Study period:
Not Reported
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original reference not available
Cross-referenceopen allclose all
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to other study

Data source

Reference
Reference Type:
review article or handbook
Title:
Nickel (II) hydroxide
Author:
NIOSH
Year:
2008
Bibliographic source:
In: Registry of Toxic Effects of Chemical Substances #QR7040000

Materials and methods

Principles of method if other than guideline:
Not Reported
GLP compliance:
not specified
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Nickel dihydroxide
EC Number:
235-008-5
EC Name:
Nickel dihydroxide
Cas Number:
12054-48-7
Molecular formula:
Ni(OH)2
IUPAC Name:
nickel(2+) dihydroxide
Details on test material:
Not Reported
- Name of test material (as cited in study report): Nickel (II) hydroxide

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified
Details on test animals or test system and environmental conditions:
Not Reported

Administration / exposure

Vehicle:
not specified
Doses:
50 mg/kg (other doses not reported)
No. of animals per sex per dose:
Not Reported
Control animals:
not specified
Details on study design:
Not Reported
Statistics:
Not Reported

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LC50
Effect level:
50 mg/kg bw
Mortality:
Not Reported
Clinical signs:
Not Reported
Body weight:
Not Reported
Gross pathology:
Not Reported
Other findings:
Not Reported

Any other information on results incl. tables

Not Applicable

Applicant's summary and conclusion

Conclusions:
Not Reported
Executive summary:

Study rated by an independent reviewer.