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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

The lowest effect values for 6PPD and the degradation products was found fo p-Hydroquinone (EC50 0.335 mg/L) and for 4HDPA (NOEC 0.23 mg/L.)

Key value for chemical safety assessment

EC50 for freshwater algae:
0.335 mg/L
EC10 or NOEC for freshwater algae:
0.23 mg/L

Additional information

Algae studies:

p-Hydroquinone is the (secondary) hydrolysis product of 6PPD. The effect concentration of this substance was used as a key value as it represents the worst case. The lowest NOEC for algae was found in a study for 4 -HDPA. Supporting information from experimental and from calculated data is given for the degradation products of 6PPD, 4 -hydroxydiphenylamine and N-phenyl-p-benzoquinone-imine. The results of these studies are effect levels higher than those stated for the key studies.

The read-across justification is attached in a separate document in chapter 13 IUCLID.