Registration Dossier
Registration Dossier
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EC number: 212-344-0 | CAS number: 793-24-8
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- other:
- Adequacy of study:
- supporting study
- Study period:
- 2012
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- The MAK Collection for Occupational Health and Safety; N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylendiamin (6-PPD) [MAK Value Documentation in German language, 2013]
- Author:
- Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area
- Year:
- 2 012
- Bibliographic source:
- MAK Value Documentation, Published Online: 22 MAY 2013; http://onlinelibrary.wiley.com/doi/10.1002/3527600418.mb79324d0055/abstract
Materials and methods
- Type of study / information:
- Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area, Occupational exposure level (MAK-value) derived
Test guideline
- Qualifier:
- no guideline followed
- Guideline:
- other: Comprehensive evaluation of all relevant data
- Principles of method if other than guideline:
- Definition
The MAK value (“maximale Arbeitsplatz-Konzentration”: maximum workplace concentration) is defined as the maximum concentration of a chemical substance (as gas, vapour or particulate matter) in the workplace air which generally does not have known adverse effects on the health of the employee nor cause unreasonable annoyance (e. g. by a nauseous odour) even when the person is repeatedly exposed during long periods, usually for 8 hours daily but assuming on average a 40-hour working week. - GLP compliance:
- no
Test material
- Reference substance name:
- N-1,3-dimethylbutyl-N'-phenyl-p-phenylenediamine
- EC Number:
- 212-344-0
- EC Name:
- N-1,3-dimethylbutyl-N'-phenyl-p-phenylenediamine
- Cas Number:
- 793-24-8
- Molecular formula:
- C18H24N2
- IUPAC Name:
- N1-(4-methylpentan-2-yl)-N4-phenylbenzene-1,4-diamine
Constituent 1
Results and discussion
Applicant's summary and conclusion
- Executive summary:
MAK defined the 8-h TWA (MAK value) to be 2 mg/m3
Exposure can be exceeded by a factor of 2 for short-term exposure
The compound should be regarded as a skin sensitizer.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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