Registration Dossier
Registration Dossier
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EC number: 211-128-3 | CAS number: 630-08-0
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Study period:
- 2012
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- As the substance is a gas, measured data for the toxicity to algae are not available. In the place of measured data, predicted data using the QSAR model ECOSAR v.1.11. The substance is within the profile of the model and so the results are considered reliable
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- other: QSAR predicted data
- Title:
- Unnamed
- Year:
- 2 012
Materials and methods
- Principles of method if other than guideline:
- ECOSAR v1.11 is a QSAR for organic substances which estimates the ecotoxicity based on structure-activity relationships.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Carbon monoxide
- EC Number:
- 211-128-3
- EC Name:
- Carbon monoxide
- Cas Number:
- 630-08-0
- Molecular formula:
- CO
- IUPAC Name:
- carbon monooxide
- Test material form:
- gas
Constituent 1
Test organisms
- Test organisms (species):
- other: Green algae, no further details
Study design
- Limit test:
- no
- Total exposure duration:
- 96 h
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- 124.4 mg/L
- Remarks on result:
- other: QSAR predicted value
Applicant's summary and conclusion
- Conclusions:
- The EC50 (96 hr) for algae was reported to be 124.4 mg/L
- Executive summary:
No experimental data are available for the effect of the substance on the toxicity to algae. The QSAR, ECOSAR Program v1.11 was used to predict the toxicity. The QSAR is acceptable with restrictions. The EC50 (96 hours) for algae is estimated to be 124.4 mg/L in fresh water
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