Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-849-4 | CAS number: 100-41-4
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Short-term toxicity test data for ethylbenzene were available for one species of marine fish and multiple species of freshwater fishes.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 4.2 mg/L
Marine water fish
Marine water fish
- Effect concentration:
- 5.1 mg/L
Additional information
Two key studies (Klimisch scores of 1 and 2) were identified and included a marine species, the Atlantic silverside (Menidia menidia) and a freshwater species, the rainbow trout (Oncorhynchus mykiss). These key studies reported 96-hr LC50 values of 5.1 and 4.2 mg/L for the silverside and rainbow trout, respectively. Four supporting studies were also identified that tested freshwater species which included Poecillia reticulata, Pimphales promelas and Cyprinodon variegatus. Endpoint values (96-hr LC50) for the supporting studies ranged from 9.6 to 49 mg/L. A total of 12 additional studies were included as supporting studies with three reported endpoints from a study considered secondary literature with a Klimisch score of 4. These endpoints were reported for Oncorynchus mykiss, Ictalurus punctatus and Lepomis macrochirus with values of 14, 88 and 210 mg/L. The remaining 9 studies had a Klimisch scores of 3 and were considered unreliable due to inadequate study designs.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
