Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 235-123-0 | CAS number: 12070-12-1
No signs of ill health or toxicity were recorded.
Body weight increases were recorded for all guinea-pigs over the period of the study.
- Necrosis was recorded at all sites receiving Freund's Complete Adjuvant in test and control animals.
- Slight to well defined irritation was seen in test animals at sites receiving Tungsten Carbide Powder-Pure, 50% w/v in Alembicol D and slight irritation was observed in control animals receiving Alembicol D.
- Slight erythema was observed in most test animals following topical application of Tungsten Carbide Powder-Pure, 75% w/v in Alembicol D. Black staining was noted over the dosed area, however, it did not interfere with scoring.
- Slight erythema was seen in most of the control guinea-pigs.
- There were no dermal reactions seen in any of the test or control animals, therefore all ten test animals gave negative responses. Black staining was observed on the dose site, however, this did not interfere with scoring.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Close Do not show this message again