Registration Dossier
Registration Dossier
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EC number: 215-236-1 | CAS number: 1314-56-3
Endpoint summary
Administrative data
Description of key information
According to EU regulation 1907/2006, Annex VII, column 2 an irritation study (skin/eye) needs not to be conducted since Diphosphorus pentaoxide is classified as corrosive to the skin.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (corrosive)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
Effects on eye irritation: highly irritating
Justification for classification or non-classification
As above mentioned no irritation studies have to be conducted with Diphosphorus pentaoxide due to its corrosive properties.
Diphosphorus pentaoxide is a hygroscopic solid which forms with moisture/water an aqueous solution of phosphorus oxyacids (primary hydrolysis) that are subject to further (secondary) hydrolysis to the end product phosphoric acid, H3PO4. The exposure to Diphosphorus pentaoxide under physiological conditions (aqueous system) will principally lead to local effects due to the strong corrosivity of the generated phosphoric acid. Consequently, the toxicity of Phosphoric acid/Diphosphorus pentaoxide, respectively is solely based on secondary effects of corrosivity.
Based on the existing data the substance is subject to classification and labelling according to Directive 67/548/EEC and Regulation 1272/2008/EC regarding corrosive prpoerties. Diphosphorus pentaoxide has to be labeled with R35 – causes severe burns; H314 - causes severe skin burns and eye damage.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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