Registration Dossier
Registration Dossier
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EC number: 232-391-0 | CAS number: 8013-07-8
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
A 48 hour static, acute toxicity study was performed according to the DIN-Vorschrift 38412-L15 (static procedure) guideline. Leuciscus iduswere exposed for 48 hours to nominal concentrations of TK 11278. Based on nominal exposure concentrations the 48 hour LC50 was calculated to be 900 mg/L, the corresponding no-observed effect concentration (NOEC) was 580 mg/L.
Key value for chemical safety assessment
Additional information
A 48 hour static, acute toxicity study was performed according to the DIN-Vorschrift 38412-L15 (static procedure) guideline. Leuciscus idus were exposed for 48 hours to nominal concentrations of TK 11278. Based on nominal exposure concentrations the 48 hour LC50 was calculated to be 900 mg/L, the corresponding no-observed effect concentration (NOEC) was 580 mg/L.
The water solubility of ESBO is estimated to be <0.02 µg/L, categorised as insoluble REACH, see section 4.8 for details. Ideally aquatic toxicity studies should not be conducted above the limit of water solubility, the study reported here tested nominal concentrations up to 1000 mg/L. According to Annex VIII a short-term test on fish is required unless there are mitigating factors such as the test substance is insoluble, this is the case for ESBO. Therefore, the fish study is reported here for information only (this study was also reported in the OECD SIDS Initial Assessment Report for SIAM 22, 18 -21 April 2006), the endpoint will not be used for PNEC setting or in any risk assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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