Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Additional information:
Migrated from Short description of key information:
No dedicated studies are available for the evaluation of the sensitising potential of HFC 125. However, no signs of skin sensitisation were observed in experimental animals exposed up to 50000 ppm HFC 125 in the atmosphere for 13 consecutive weeks.

Respiratory sensitisation

Endpoint conclusion
Additional information:
Migrated from Short description of key information:
No dedicated studies are available for the evaluation of the sensitising potential of HFC-125. However, no signs of respiratory sensitisation were observed in experimental animals exposed by inhalation up to 50000 ppm HFC-125 in the atmosphere for 13 consecutive weeks.

Justification for classification or non-classification

HFC-125 can be considered as a non-sensitising substance and no classification is deemed necessary.