Registration Dossier
Registration Dossier
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EC number: 257-098-5 | CAS number: 51274-00-1 This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 77492.
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: scientifically acceptable and sufficient documented
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 977
- Report date:
- 1977
Materials and methods
- Principles of method if other than guideline:
- Single oral application by means of gavage
- GLP compliance:
- not specified
- Limit test:
- yes
Test material
- Reference substance name:
- Iron hydroxide oxide yellow
- EC Number:
- 257-098-5
- EC Name:
- Iron hydroxide oxide yellow
- Cas Number:
- 51274-00-1
- Molecular formula:
- Fe(OH)O
- IUPAC Name:
- Iron hydroxide oxide
- Test material form:
- solid: nanoform
- Details on test material:
- FeOOH (Eisenoxidgelb 920)
- Density: 4.1 g/mL
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- water
- Doses:
- 10 g/kg
- No. of animals per sex per dose:
- 10
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- > 10 000 mg/kg bw
- Clinical signs:
- other:
Applicant's summary and conclusion
- Executive summary:
- 10 animals were treated with 10000 mg/kg bw of the test substance. During an observation time of 14 days none of the animals showed signs of toxicity or died.
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