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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

Key value for chemical safety assessment

Additional information


From the database of acute toxicity to freshwater invertebrates, there are many high quality studies which predominantly report the 48h LC50as the endpoint. Many species are represented in these studies, dominated byDaphnia magnaandCeriodaphnia dubia.  The 48h LC50s values range from 0.013 mg Ni/L (Ceriodaphnia dubia; Schubauer-Berigan et al., 1993) to 4970 mg Ni/L (Daphnia magna; Chapman and Recht, 1980).


From the database of acute toxicity to marine invertebrates, there are many high quality studies which report predominantly 48h LC50and 48h EC50as the endpoint, representing many species. The 48h LC50s values range from 0.23 mg/L (Haliotis refescens; Hunt et al., 2002b) to 415 mg/L (Penaeus duorarum; Bentley et al., 1975b). The 48h EC50values range from 0.15 mg/L (Mytilus trossulus; Nadella et al., 2009) to 4.66 mg/L (Artemia salina; Kissa et al., 2002b).

As the PNEC intermittent endpoint is not relevant for the identified processes, no short-term tests are used in any PNEC derivation.