Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 265-043-1 | CAS number: 64741-43-1 A complex combination of hydrocarbons produced by the distillation of crude oil. It consists of hydrocarbons having carbon numbers predominantly in the range of C11 through C25 and boiling in the range of approximately 205°C to 400°C (401°F to 752°F).
Repeated dose toxicity: oral
Administrative data
- Endpoint:
- short-term repeated dose toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- Studies to be scheduled: initial studies planned to start in Q1 2018 with results available in Q4 2018
- Justification for type of information:
- These studies are planned to be conducted as part of the overall Concawe testing strategy for petroleum substances and the OGO category and one substance will also act as a range-finders for an OECD 443 study (subject to test proposal acceptance). More detail on the overall testing strategy is available in the document attached in Section 13 of this dossier.
The aim of these studies is:
- act as a range finding study for a planned OECD 443 study
- provide information on repeat-dose toxicity by the oral route
- provide support for the existing historical testing database (primarily via the dermal route of exposure)
- provide support for category read-across
Substances will be chosen for testing based on high levels of PAC content and for comparison with exiting data.
Data source
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 422 (Combined Repeated Dose Toxicity Study with the Reproduction / Developmental Toxicity Screening Test)
Test material
- Reference substance name:
- Distillates (petroleum), full-range straight-run middle
- EC Number:
- 272-341-5
- EC Name:
- Distillates (petroleum), full-range straight-run middle
- Cas Number:
- 68814-87-9
- IUPAC Name:
- Distillates (petroleum), full-range straight-run middle
Constituent 1
- Specific details on test material used for the study:
- Test material is an example of one of the substances expected to be used in the planned studies.
Test animals
- Species:
- rat
Administration / exposure
- Route of administration:
- oral: feed
Results and discussion
Effect levels
- Dose descriptor:
- other: results not yet available
- Remarks on result:
- other: study planned; results not yet available
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
