Registration Dossier
Registration Dossier
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EC number: 233-140-8 | CAS number: 10043-52-4
Repeated dose toxicity: inhalation
Administrative data
- Endpoint:
- repeated dose toxicity: inhalation
- Adequacy of study:
- other information
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: Documentation insufficient for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Toxicological assessment of calcium chloride and calcium chloride-containing products
- Author:
- Sukhanov, V.V., Petul'ko, S.N., Bolonova, L.N. and Yulish, N.R.
- Year:
- 1 990
- Bibliographic source:
- Gigiena Truda I Professional'nye Zabolevaniya (Labor Hygiene and Occupational Diseases), 34(5), 51-52
Materials and methods
- Principles of method if other than guideline:
- Method: other
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Calcium chloride
- EC Number:
- 233-140-8
- EC Name:
- Calcium chloride
- Cas Number:
- 10043-52-4
- Molecular formula:
- CaCl2
- IUPAC Name:
- calcium dichloride
- Details on test material:
- Test substance: technical grade
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation
- Duration of treatment / exposure:
- 4 months, 4 hours/day
- Frequency of treatment:
- 5 days/week
Doses / concentrations
- Remarks:
- Doses / Concentrations:
8.5, 14.9, 43.1 mg/m³
Basis:
- Control animals:
- other: no data specified
Results and discussion
Effect levels
- Effect level:
- 8.5 mg/m³ air
- Sex:
- not specified
Target system / organ toxicity
- Critical effects observed:
- not specified
Applicant's summary and conclusion
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