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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Dissociation constant

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data from peer-reviewed handbook or collection of data
Principles of method if other than guideline:
no data
GLP compliance:
not specified
Dissociating properties:
yes
No.:
#1
pKa:
4.34
Temp.:
18 °C
Remarks on result:
other: Solvent: water; Method: potentiometric
No.:
#2
pKa:
5.44
Temp.:
18 °C
Remarks on result:
other: Solvent: water; Method: potentiometric
No.:
#1
pKa:
4.43
Temp.:
20 °C
Remarks on result:
other: Solvent: water; Method: potentiometric
No.:
#2
pKa:
5.42
Temp.:
20 °C
Remarks on result:
other: Solvent: water; Method: potentiometric
No.:
#1
pKa:
4.43
Temp.:
25 °C
Remarks on result:
other: Solvent: water; Method: potentiometric and conductometric
Executive summary:

The dissociation constants of adipic acid are pK1= 4.43 and pK2= 5.42 at 20 °C (Beilstein, 2003).

Description of key information

The dissociation constants of adipic acid are pK1 4.43 and pK2 5.42 at 20 °C (Beilstein, 2003). 

Key value for chemical safety assessment

Additional information