Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
health surveillance data
Type of information:
other: data from report on workplace safety
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1983

Materials and methods

Study type:
biological exposure monitoring
Endpoint addressed:
skin irritation / corrosion
skin sensitisation

Test material

Constituent 1
Chemical structure
Reference substance name:
disodium oxo[(oxoalumanyl)oxy]alumane silanedione hydrate oxidandiide
EC Number:
930-915-9
Cas Number:
1318-02-1
Molecular formula:
M2/nO • Al2O3 • ySiO2 • wH2O (n is the valency of the cation M, predominantly Na, y can range from 0.64 to 8.8, and w is the number of water molecules (general formula) Na: 1.34 - 24.02%, Al: 2.20 - 39.51%, Si: 15.52 - 68.64% (general composition); additionally, depending on the water quality: Ca, Mg and K might be present below 6%
IUPAC Name:
disodium oxo[(oxoalumanyl)oxy]alumane silanedione hydrate oxidandiide
Test material form:
solid: particulate/powder
Remarks:
no surface treatment
Specific details on test material used for the study:
Zeolite A, 1% application

Method

Details on study design:
In a human study a 1% suspension of Zeolite A was tested on the back of 100 subjects with irritable skin, using a 24-hr patch-test procedure.

Results and discussion

Results:
Human skin tolerated without reaction a 24-hr exposure to a 1% Suspension of Zeolithe A in a patch test.

Applicant's summary and conclusion

Conclusions:
Human skin tolerated without reaction a 24-hr exposure to a 1% Suspension of Zeolithe A in a patch test.
Executive summary:

In a human study a 1% suspension of Zeolite A was tested on the back of 100 subjects with irritable skin, using a 24-hr patch-test procedure. No skin irritation was observed.