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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
up to 2006
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: GLP status not known, guideline not known, information from a published handbook, acceptable with restrictions

Data source

Reference
Reference Type:
review article or handbook
Title:
The Merck Index. An encyclopedia of chemicals, drugs and biologicals. Fourteenth Edition.
Author:
O'Neil MJ (Ed.)
Year:
2006
Bibliographic source:
Merck & Co, Inc. Whitehouse Station, NJ, USA

Materials and methods

Principles of method if other than guideline:
The use of secondary sources of data is acceptable when they are based on a critical evaluation of peer-reviewed data and a consequent selection of a reliable and representative value for the property under investigation. The introduction to the Merck Index states that physical data are cited as found in the literature. When several alternate data values appear in the literature, the data is evaluated and representative selections are made; values are then reported with the corresponding source. Therefore, although the method used is not known, the values presented here are acceptable as they are from a reliable secondary source of phys chem. data.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Cyclohexane
EC Number:
203-806-2
EC Name:
Cyclohexane
Cas Number:
110-82-7
Molecular formula:
C6H12
IUPAC Name:
cyclohexane

Results and discussion

Solubility in organic solvents / fat solubility
Medium:
methanol
Solubility:
570 g/L
Temp.:
20 °C
Test substance stable:
yes

Applicant's summary and conclusion

Conclusions:
The solubility of the test substance in methanol is 570g/L under the temperature of 20°C.
Executive summary:

The solubility of the test substance in methanol is 570 g/L under the temperature of 20°C. No information on the primary source of this data or the methods used is available. However, this information is taken from a reliable peer reviewed handbook and so can be considered reliable and suitable for use as the supporting study for this endpoint.