Registration Dossier
Registration Dossier
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EC number: 211-309-7 | CAS number: 637-92-3
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The 21-d NOEC for MTBE in Daphnia magna is 51 mg/l, applying a safety factor of 10 results in a NOEC of 5.1 mg/l for ETBE. For marine invertebrates the 28-d NOEC for TAME is 3.39 mg/l in Americamysis bahia, applying a safety factor of 2 results in an NOEC of 1.7 mg/l for ETBE.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 5.1 mg/L
Marine water invertebrates
Marine water invertebrates
- Effect concentration:
- 1.7 mg/L
Additional information
No chronic studies with invertebrates are available for ETBE, chronic studies are, however, available for MTBE and TAME. A guideline study is available for MTBE withDaphnia magna, the 21-d NOEC is 51 mg/l (Wildlife International Ltd. 1999). A safety factor of 10 is applied to this value, resulting in an effect concentration of 5.1 mg/l for ETBE. For marine invertebrates a chronic guideline study is available for TAME withAmericamysis bahia(T.R. Wilbury Laboratories, Inc., 2004). The 28-d NOEC is 3.39 mg/l, applying a safety factor of 2 results in an effect concentration of 1.7 mg/l for ETBE. These values are used in the assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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